Lung involvement in the anti-TIF1γ(+) group encompassed 1 case with NSIP, 1 with honeycombing and 1 with profound emphysema and no cases with UIP compared to 32, 2, 1 and 13 cases in the anti-TIF1γ(−) group, respectively (p<0.004). Here, TRIM33 is linked to pulmonary emphysema.