HP and cancer: This score assigns one point for each of the following criteria: hemolysis (reticulocyte count >2.5%, total bilirubin >2.0 mg/dL, or decreased haptoglobin), mean corpuscular volume (MCV) <90 fL, international normalized ratio (INR) <1.5, serum creatinine <2.0 mg/dL, absence of active cancer, and no history of solid organ or stem cell transplantation.