Specific gene alterations in cancer and cellular senescence were noted, including downregulation of wingless-type MMTV integration site 2 (WNT2, FC = −2.8, FDR < 1.0e−140) and heat shock protein 90kDa alpha (cytosolic) A1 (HSP90AA1, FC = −0.67, FDR < 2.0e−20), and upregulation in signal transducer and activator of transcription 2 (STAT2, FC = 0.6, FDR < 5.0e−08) and human leukocyte antigens A (HLA-A, FC = 0.38, FDR < 3.0e−05) (Figure 2F, Supplementary Figure S2b). This evidence concerns the gene HSP90AA1 and cancer.