Further evaluation of the effects of THM on cell proliferation, autophagy, and the m6A reader protein YTHDF2 by immunohistochemistry (IHC) analysis revealed that THM decreased the expressions of Ki-67 and YTHDF2, and increased the expressions of ATG5, ATG7, and LC3B (Figure 7K-L), suggesting a possible mechanism by which THM inhibits the growth of pancreatic cancer. The gene discussed is ATG5; the disease is familial pancreatic carcinoma.