For instance, Michaelsen et al. reported a clinical study involving patients with advanced prostate cancer, where the long-term addition of Artemisiae Annuae Herba following short-term treatment with bicalutamide led to tumor regression and treatment remission, as confirmed by prostate-specific antigen (PSA), magnetic resonance imaging, and SPECT/CT indicators 122. Here, KLK3 is linked to Familial prostate cancer.