Furthermore, using TCGA datasets, we performed correlation analysis between the expression levels of CXCL12, CXCR4, M2 macrophage-associated molecules (IL10, TGFB1), and tumor invasion-associated molecules (S100A8, S100A9, MMP2, MMP7, MMP9) in peritumor tissues. The gene discussed is S100A8; the disease is neoplasm.