TNF and pemphigus foliaceus: In another study, Peimine relieves BLM-induced PF by upregulating E-cadherin and downregulating vimentin, while also reducing the expression of interleukin-1β (IL-1β), interleukin-6 (IL-6), and TNF-α, increasing SOD and GPX activities, and lowering MDA levels in the lungs (Li L. et al., 2023).