The hallmark features of PD are the degeneration of dopaminergic neurons in the substantia nigra pars compacta (SNc), along with accumulation of aberrant alpha-synuclein (α-syn), often in the form of Lewy bodies and Lewy neurites (Stefanis, 2012; Samii et al., 2004; Gómez-Benito et al., 2020). The gene discussed is SNCA; the disease is Parkinson disease.