CXCL8 and clostridium difficile infection: Some scholars have evaluated 17 biomarkers in the serum of patients with CD colitis, and logistic regression analysis shows that, IL-6, Procalcitonin, IL-8, IL-2R, and hepatocyte growth factor are significantly correlated with adverse outcomes of CDI (13), but the validation of biomarkers related to rCDI was still relatively lacking.