Glycoprotein signals (GlycA, GlycB, Glyc), which reflect the glycosylation patterns of circulating acute-phase inflammatory proteins, especially fibrinogen, α1-antichymotrypsin, haptoglobin-1, α1-antitrypsin, complement C3, and α1-acid glycoprotein [[59], [60], [61]], were significantly reduced in T1DM participants. Here, ART4 is linked to type 1 diabetes mellitus.