Several factors, including the hypoxic conditions of tumor cells, the inflammatory state of the body, and the activation of oncogenic signaling pathways (e.g., MYC and PI3K) (8), influence the quantity of glucose transporters and the expression and activity levels of key glycolysis-related enzymes (such as phosphofructokinase and hexokinase), thereby affecting the glycolytic rate. This evidence concerns the gene MYC and neoplasm.