The majority of CRC cases are due to altered KRAS and B‐Raf, which activate WNT‐APC‐CTNNB1, PI3K, TGFB1‐SMAD, and RAS–RAF–MAPK pathways and promote proliferation with suppressed apoptosis (Ahronian et al. 2015). This evidence concerns the gene KRAS and colorectal carcinoma.