VEGFA and diabetes mellitus: It is important to emphasize that, unlike the changing pattern of CGRP+ nerves, the expression of VEGF in the periodontium is significantly higher in diabetes‐associated periodontitis patients compared to healthy individuals or patients with periodontitis alone.[48] Therefore, the impaired formation of type H vessels in diabetes‐associated periodontitis is not due to a lack of VEGF but rather results from insufficient CGRP signaling.