Independent of infection status, there were no differences between the three groups in the total numbers of PleC or tLN cells (Figure S6A,B), PleC or tLN CD4+ T cells (Figure S6C,D), PleC Foxp3+ Tregs (Figure S6E), or tLN CXCR5+ Tfh cells (Figure S6F). This evidence concerns the gene FOXP3 and infection.