Similar results were found in BAP1-deficient cholangiocarcinoma TFK-1 cells (Figure S2A-C), UM UPMM2 cells (Figure S2D,E), breast cancer HCC-1187 cells (Figure S2F,G), and ccRCC 786–0 cells with wild-type BAP1 knocked out using two different CRISPR-Cas9 guided-RNAs (Figure S2H). This evidence concerns the gene BAP1 and cholangiocarcinoma.