Oncogenic tyrosine kinases are involved in the regulation of autophagy in several cancers through BECN1 (BCL2 interacting myosin like coiled protein) phosphorylation [32], including EGFR (epidermal growth factor receptor) in non-small cell lung cancer [33], HER2/ERBB2 (human epidermal growth factor receptor 2) in breast cancer [34], BCR-ABL (breakpoint cluster region-ABL proto-oncogene 1 non-receptor tyrosine kinase) in chronic myeloid leukemia [35], and c-KIT in Merkel cell carcinoma [36]. Here, BECN1 is linked to Merkel cell skin cancer.