There was a mild renal insufficiency in both groups with a lower glomerular filtration rate (GFR) in the no-SGLT2-i group compared to the SGLT2-i group (78 [57.5–94] vs. 69.8 [50–88.2] ml/min/1.73 m2, p = 0.017). Here, SLC5A2 is linked to Renal insufficiency.