KLC1 and schizophrenia: We strengthen the evidence for an allelic series of common and rare schizophrenia risk alleles in STAG1, and provide evidence for the convergence of common and rare risk alleles in KLC1. Association of STAG1 at exome-wide significance provides further support for an aetiological role of disrupted chromatin organisation in schizophrenia, while association of SLC6A1 at FDR < 5% furthers the evidence implicating perturbed GABAergic neuronal signalling in the disorder.