We performed immunohistochemistry of control and IPF tissue and, confirming the scRNASeq data, found increased active, nuclear YAP expression predominantly in alveolar epithelial cells associated with regions of visible epithelial remodeling, while TAZ expression was found mainly in mesenchymal cells in fibrosis (Fig. 1B and Supplementary Fig. S1A) which matches other previous reports which focused on TAZ activity in fibroblasts24,25. Here, YAP1 is linked to idiopathic pulmonary fibrosis.