CCN2 and idiopathic pulmonary fibrosis: Our single cell RNA sequencing (scRNASeq) dataset revealed cell-type specific gene expression of YAP, TAZ, and YAP target genes in alveolar epithelial cells with YAP as the highest expressed transcriptional coregulator of the Hippo pathway in alveolar epithelial cells, and increased expression of the YAP target gene connective tissue growth factor (CTGF) in transitional/aberrant alveolar epithelial cells in IPF, further indicating YAP activity is increased in IPF (Fig. 1A)22,23.