This rare condition typically presents with a specific immunophenotypic profile (CD117 +  +, tryptase +  +, CD11b −, CD123 −, CD2 −, CD25).While MML features can occur in various myeloid neoplasms, its presentation as a blast phase manifestation of CML is exceptionally rare [6, 7]. The gene discussed is CD2; the disease is myeloid neoplasm.