For example, no tumors had SMARCB1 or SMARCA4 alterations characteristic of ATRT, no tumors had histone H3 mutations characteristic of diffuse midline or hemispheric gliomas in children, and no tumors had C19MC amplification or DICER1 mutation characteristic of embryonal tumor with multilayered rosettes (ETMR). The gene discussed is DICER1; the disease is embryonal neoplasm.