Pancreatic cancer progression is closely associated with inflammation, and we previously showed that short hairpin RNA‐mediated knockdown of sST2 expression, a soluble decoy receptor for the proinflammatory molecule interleukin‐33 (IL‐33), in mouse Panc02 pancreatic cancer cells reduced malignant growth following pancreatic (orthotopic) implantation. The gene discussed is IL33; the disease is familial pancreatic carcinoma.