CTHRC1 and familial pancreatic carcinoma: To further explore the specific role of CAFs in pancreatic cancer and its important molecules, we first analyzed the single‐cell sequencing results [17] by bioinformatics analysis and found that CTHRC1 was significantly overexpressed in CAFs of pancreatic cancer, which was significantly higher than its expression level in pancreatic cancer cells and other cells (Figure 1A,B).