STAT3 and familial pancreatic carcinoma: Subsequent coculture of pancreatic cancer cells with CTHRC1‐knockdown CAFs‐CM and CTHRC1‐reconstituted‐overexpressing CAFs‐CM demonstrated that CAF‐derived CTHRC1 promotes epithelial‐mesenchymal transition and positively regulates STAT3 signaling pathway activation in cancer cells.