CAFs with CTHRC1 knockdown or overexpression were cocultured with pancreatic cancer cells, and the CCK‐8 cell proliferation assay showed that knockdown of CTHRC1 in CAFs significantly inhibited pancreatic cancer cell proliferation (Figure 2D–F), whereas overexpression of CTHRC1 in CAFs significantly promoted pancreatic cancer cell proliferation (Figure 2G). The gene discussed is CTHRC1; the disease is familial pancreatic carcinoma.