Mitochondrial fission regulator 2 (MTFR2), ADP-ribosylation factor 1 (ARF1), and the ovarian tumor-associated protease deubiquitinase 6 A (OTUD6A) are also significantly overexpressed in CRC tissues, suggesting their potential roles in mitochondrial dynamics and cancer progression [167–169]. Here, ARF1 is linked to cancer.