Patients with available NT-proBNP concentrations vs those without tended to be older (65 vs 63 years, P = 0.085), were more likely to be male (65 vs 57%, P = 0.005), have atrial fibrillation (4.4% vs 0.7%, P < 0.001), heart failure (1.5% vs 0.3%, P = 0.056), and coronary artery disease (5.6% vs 2.2%, P = 0.003) (Supplemental Table 1), but had similar event rates of acute cardiovascular hospitalizations and death (KM event rates at 12 months: 29% vs 32%, P = 0.52). This evidence concerns the gene NPPB and coronary artery disorder.