ACHE and Alzheimer disease: The findings of this investigation indicated that AST and AST-LI may function as inhibitors of AChE and MAO enzymes, as indicated by restoring the neurotransmitter balance via raising serotonin levels and decreasing AChE and MAO activities, thereby improving cognitive performance in behavioral (SAP, DI, and DR) scores compared to AD-like rats (Figs. 5 and 6).