NPHS1 and HIV-associated nephropathy: A study using nephrin promoter-driven APOL1-G0 Tg mice crossbred with HIV-Tg26 mice showed that fewer renal HIVAN lesions were developed compared to single HIV-Tg26 mice, suggesting a protective role for APOL1-G0 against HIV-induced nephropathy (Zhang et al., 2013).