NLRP3 and tuberculosis: Cytokines and chemokine analysis of lung homogenates from wild-type and Nlrp3−/− Mtb-infected mice at day 14 revealed that several TB immunity-associated cytokines, such as TNFα, did not vary by condition, whereas others, such as IL-6 varied between wild-type and Nlrp3−/− mice, but not in a PstS1 mAb-specific manner (Extended Data Fig. 2).