Because both PARK7 and HNRNPA2B1 showed better diagnostic performance than the other genes in the area under the ROC curve (AUC) assessment (AUC = 0.745) and also had a strong influence in terms of statistical significance (P value), In addition, there is sufficient biological evidence in the postpartum depression (PPD) literature to support its importance in the disease mechanism, especially its key role in neuroprotection and cell signaling. Here, HNRNPA2B1 is linked to progressive pseudorheumatoid arthropathy of childhood.