SHBG and polycystic ovary syndrome: The highest calculated FT levels were observed in typical patients with PCOS and abnormal glucose tolerance, followed by their normoglycemic counterparts and then by women with T1D and PCOS (Fig. 2); these differences were mirrored by SHBG concentrations, which were normal in women with T1D and PCOS but were decreased in typical patients with PCOS, particularly in those with abnormal glucose tolerance (Fig. 2).