GRIN2D and breast cancer: The METTL3/YTHDF2-mediated m6A regulatory axis promotes BC cell invasiveness by degrading the tumor-suppressive factors SET domain containing lysine methyltransferase 7 and Krüppel-like factor 4, thereby diminishing their tumor-suppressive functions.36 In addition, YTHDF1 stabilizes glutamate [NMDA] receptor subunit epsilon-4 (GRIN2D) mRNA by binding to its m6A sites in BC, preventing GRIN2D degradation and elevating its expression.