TRMT6 and breast cancer: The depletion of TRMT6/TRMT61A slows the average migration speed of 5,637 cells, potentially impacting cell migration ability.78 BC cells with high m5C expression, particularly muscle-invasive BC cells, exhibit higher methylation levels and increased invasiveness.57 Ying et al. 73 demonstrated that the loss of METTL1 significantly suppresses BC cell migration, invasion, and distant metastasis.