However, WTAP-mediated downregulation of SYTL1 enables BC cells to evade NK cell attacks, providing a proliferation and invasion advantage in the immune environment.21 In addition, YTHDC1 deficiency may modulate immune cell infiltration in the TME, particularly promoting the accumulation of M2 macrophages, which indirectly supports BC growth and invasion.27 The gene discussed is YTHDC1; the disease is breast cancer.