METTL3 and breast cancer: Studies have demonstrated that the m6A methyltransferase METTL3 is upregulated in BC, facilitating tumor cell proliferation and invasion.18 METTL3 regulates oncogenes such as MYC, ALF transcription elongation factor 4, and v-rel avian reticuloendotheliosis viral oncogene homolog A by modulating their m6A levels.