YTHDC1 and neoplasm: YTH m6A RNA binding protein (YTHDF) 1, YTHDF2, and YTHDF3 are key m6A-binding proteins that specifically recognize m6A-modified RNA through particular domains, affecting its stability and translation.24 The YTHDF protein family, characterized by their YT521 homology (YTH) domains,16,21,25 recognizes m6A-modified RNA and regulates various mRNAs linked to tumor progression, with significant biological implications.