Both duration of Li administration (hyper i-PTH: ρ = 0.260,p=0.010 and hypercalcemia: ρ = 0.206,p=0.044) and serum Li concentration (hyper i-PTH: ρ = 0.274,p=0.006 and hypercalcemia: ρ = 0.232,p=0.022) showed significant and positive associations with hyper i-PTH and hypercalcemia (Table 4). This evidence concerns the gene PTH and hypercalcemia disease.