Both CRP at time of early brain injury (reflected by the day 1 assay) and on day 28 were associated with fatigue, but not CRP at time of delayed brain injury or complications related to hospitalisation (on day 7), contrary to previous studies (de Rooij et al., 2013; Fountas et al., 2009; Hwang et al., 2013). This evidence concerns the gene CRP and injury.