VPS37A and neoplasm: GSEA revealed suppression of G2/M CHECKPOINT (NES = −2.16, p < 0.05) and E2F TARGETS (NES = −2.02, p < 0.05), while KEGG analysis showed inhibition of CELL CYCLE pathways (NES = −1.77, p < 0.05), aligning with VPS37A’s tumor-suppressive role (Fig. 5D,E).