VPS37A and colorectal carcinoma: PI staining demonstrated that VPS37A overexpression significantly enhanced CRC cell death under these two stress conditions in both SW620 (GA, p < 0.05; GD, p < 0.01) and DLD-1 (GA, p > 0.05; GD, p < 0.01) cells (Fig. 4H and Supplementary Fig. S2).