For analyzing the role of USP13 in the angiogenesis of CRC tumors, we established stable knockdown cell lines, namely sh-USP13-HCT116 and sh-USP13-HT29, and stable overexpression cell lines, namely Flag-USP13-HCT116 and Flag-USP13-HT29, through lentiviral infection. The gene discussed is USP13; the disease is infection.