In TNBC, protein kinase D3 (PKD3) (localized in the GA) is highly expressed in cancer samples and can provide a molecular link between the GA and endolysosomes to enhance the transduction of proliferation signals, like mechanistic target of rapamycin complex 1-ribosomal protein S6 kinase 1 (mTORC1-S6K1) [14]. This evidence concerns the gene PRKD3 and cancer.