FOXP3 and cancer: There is much evidence for the biology studies of T-ALL and the use of the Jurkat cell line, mainly for apoptosis, T-cell activation, and signal transduction [15]; also, Jurkat cells express the transcription factor forkhead-box-protein P3 (FOXP3), which has been reported to control many pro-oncogenic properties conferring aggressiveness in cancer cells, and poor prognosis in patients [16].