FOXP3 and cancer: It has been reported that ROS exerts a regulatory response in key transcription factors related to transformed T lymphocytes, such as FOXP3 [20,21]; the human protein atlas (proteinatlas.org) shows the high relevance of FOXP3 expression in different cancer cells, including leukemia (arrow, Fig. 3A), and Jurkat cells positions as a cell line with high expression of this transcription factor (arrow, Fig. 3B) [22].