An AD module score was then calculated based on the expression levels of key AD-related genes (CCL27, CD74, IFITM3, IFNG, KRT6A, S100A7, S100A8, S100A9, and SERPINB4), revealing a clear distinction between control and AD samples (Figures 4B,C). The gene discussed is SERPINB4; the disease is Alzheimer disease.