12-O-tetradecanoylphorbol 13-acetate induces the formation of a heterodimer of NR4A1 with RXRα (NR4A1/RXRα heterodimer), leading to the translocation of NR4A1/RXRα heterodimer to mitochondria in the human prostate adenocarcinoma cell line LNCaP. The gene discussed is RXRA; the disease is prostate adenocarcinoma.