Of those, the strongest effects were observed for HLA-A*03:01, HLA-A*37:01, HLA-B*07:02, HLA-B*15:01, HLA-B*37:01, HLA-C*07:02, Some of these alleles (e.g., HLA-A*03:01 and HLA-B*07:02)39 have previously been shown to be associated with MS risk though the findings have been inconsistent particularly with regard to whether the associations with disease are independent or accounted for by linkage disequilibrium with other alleles (e.g., DRB1*15:01)17. The gene discussed is HLA-C; the disease is myeloid sarcoma.