AKT1 and nasopharyngeal carcinoma: Pathway enrichment analysis of the 159 key proteins identified from the intersection of NPC-related genes, QZD treatment targets, and high-risk locally advanced NPC-associated genes revealed that the primary intervention pathways of QZD in high-risk locally advanced NPC patients include Apoptosis, PI3K-Akt signaling pathway, Th17 cell differentiation, C-type lectin receptor signaling pathway, Thyroid hormone signaling pathway, EGFR tyrosine kinase inhibitor resistance, Proteoglycans in cancer, Endocrine resistance, Prostate cancer, and Lipid and atherosclerosis (Figure 3a).