Findings indicate that the CML microenvironment employs immune evasion modulation that promotes the apoptosis of CD8+CD26hi T cells through the galectin-9 (Gal-9)/TIM-3 axis, leading to a pronounced depletion of this subset occupying the majority of MAIT cells (58). The gene discussed is LGALS9; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.