MPST is expressed in a variety of cancer tissues, such as glioblastoma, lung cancer, colon cancer, head and neck squamous cell carcinoma, liver cancer, pancreatic cancer, renal cell carcinoma, etc., and the expression level and prognostic significance of MPST are different in different cancers, suggesting that MPST may be a cancer-related gene (17). Here, MPST is linked to hereditary clear cell renal cell carcinoma.