ITGA2B and enterocolitis: To localize platelet-monocyte aggregates in Necrotizing Enterocolitis (NEC) lesions, we first immunostained the tissue samples of uninflamed premature intestine (that had been surgically resected for conditions other than NEC) as well as human NEC samples for the platelet antigen CD41/GPIIb, CD14, and integrin-β3.