In addition, although CD45 was unchanged with APX3330 treatment, the CD45 antibody stains T and B cells very strongly, while macrophages and neutrophils, which are stained more weakly (Stupka et al., 2000), yet in DMD muscles, the predominant inflammatory cell populations are macrophages and neutrophils. This evidence concerns the gene PTPRC and Duchenne muscular dystrophy.