promoted in their work the theory that an angiogenic imbalance in the setting of a preeclampsia/HELLP syndrome, involving increased sFlt‐1 and decreased PlGF, may lower CFH levels, resulting in complement dysregulation, an increase in endothelial C5b‐9 deposition and generating persistent endothelial dysfunction (Matsuyama et al. 2021). This evidence concerns the gene PGF and HELLP syndrome.