Plus, collapsed glomerular glycocalyx (heparan sulfate, syndecans...) seems to be responsible for secondary hypertension (Milusev et al. 2022; Ramnath et al. 2020), significant proteinuria and increase in uremic toxins, that match the symptoms of preeclampsia (Butler et al. 2020; Padberg et al. 2014; Singh et al. 2007; Nieuwdorp et al. 2006). This evidence concerns the gene SDC1 and Hypertension.