PARP1 and infection: In line with this, infection of balloon-injured arteries with adenovirus encoding shRNA against PARP1 (PARP1 shRNA) versus scramble shRNA reserved the expressional alteration of genes involved in contraction, suppressed the genes in migration and proliferation (Fig. 2a) and attenuated the neointima/media ratio (day 14) (Fig. 2b).