MYOCD and infection: Here, infection with Ad-myocardin versus Ad-Null suppressed the luciferase activities driven by WT, but not by AP1-binding site-mutated (MUT), promoters of CyclinD1 and MMP9 genes (targets of c-Jun, respectively) (Fig. 7c and Supplementary Fig. 7a), indicating that overexpression of myocardin suppressed c-Jun-dependent promoter activation.