,12 Previous studies have shown that lower haptoglobin levels in septic patients are associated with higher mortality rates13,14 and that admission haptoglobin concentrations have been shown to predict AKI in patients undergoing cardiac surgery, as well as those with Acute Respiratory Distress Syndrome(ARDS) or severe burns.15, 16, 17, 18 However, research on its correlation with sepsis-associated AKI is still scarce. The gene discussed is HP; the disease is acute kidney injury.