Shaikh et al. have concluded that temperature ≥ 39 °C, any pathogen other than Escherichia coli, abnormal ultrasonographic findings, polymorphonuclear cell count ≥ 60%, C-reactive protein (CRP) ≥ 40 mg/L, and the presence of VUR ≥ third grade were associated with the development of kidney scarring in pediatric patients with a first UTI [9]. Here, CRP is linked to bacterial urinary tract infection.