Patients with Sheehan syndrome, compared with healthy controls, had significantlyhigher mean TNF-α levels (23.41 ± 10.97 pg/mLversus 20.05 ± 2.76 pg/mL; p = 0.041) and mean IL-6levels (37.19 ± 5.38 pg/mL versus 32.08 ± 1.18pg/mL; p = 0.004). This evidence concerns the gene TNF and Sezary syndrome.