Furthermore, KMT2B overexpression also significantly increased the tumour burden in orthotopic tumour models of PANC‐1 (.56 ± .14 g vs.  .75 ± .14 g, p < .05, Figure 3D,F) and CFPAC‐1 cells (.61 ± .09 g vs.  .89 ± .16 g, p < .05, Figure 3E,F; independent replicate experiment:  .43 ± .09 g vs.  .54 ± .18 g, p < .05, Figure S6A). Here, KMT2B is linked to neoplasm.